Abstract: Liver fibrosis can progress to severe hepatic conditions, including cirrhosis and hepatocellular carcinoma, as it continues to develop. Timely and accurate diagnosis is crucial; however, ...

This study presents valuable findings implicating nuclear export in the regulation of protein condensate behaviour and TDP-43 phase behaviour, suggesting a link to pathogenic aggregation in ALS/FTD.

Background Patients with heart failure (HF) frequently suffer from undetected declines in cardiorespiratory fitness (CRF), which significantly increases their risk of poor outcomes. However, current ...