This discussion has been edited for length and clarity. Three clinicians explore the headline-making evidence from the monarchE and NATALEE trials presented at the 2025 ESMO Congress. Laura A. Huppert ...

In a phase 3 trial-based cost-effectiveness analysis for advanced breast cancer, treatment with cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors in the second line rather than the first line ...

In Sarah Yuska’s sixth-grade science class at Monocacy Middle School in Frederick, Maryland, students are just finishing up learning about body systems—respiratory, circulatory, skeletal, and so on.

In forecasting economic time series, statistical models often need to be complemented with a process to impose various constraints in a smooth manner. Systematically imposing constraints and retaining ...

Hello! I'm a dreamer focusing on high-load distributed systems and low-level engineering. I mainly code in Rust and Python ...

String manipulation is a core skill for every Python developer. Whether you’re working with CSV files, log entries, or text analytics, knowing how to split strings in Python makes your code cleaner ...

JSON Prompting is a technique for structuring instructions to AI models using the JavaScript Object Notation (JSON) format, making prompts clear, explicit, and machine-readable. Unlike traditional ...

Multiplication in Python may seem simple at first—just use the * operator—but it actually covers far more than just numbers. You can use * to multiply integers and floats, repeat strings and lists, or ...

For patients with HR-positive breast cancer, adverse effects vary by CDK4/6 inhibitor, says Courtney Moore, APRN, FNP-C, OCN. For patients with hormone receptor (HR)–positive breast cancer, CDK4/6 ...