Scientists profiling small non-coding RNAs in postmortem brain tissue from people with schizophrenia and bipolar disorder have identified sweeping molecular disruptions that extend well beyond the ...

Once considered cellular junk, non-coding RNAs are emerging as key players in everything from brain development to cancer — ...

To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in disease progression. Disrupt them and negate whatever role they play in ...

Small RNAs play a major role in schizophrenia and bipolar disorder. Specific RNA profiles show distinct changes in the brain, especially in younger people.

Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with night blindness in youth and progresses to tunnel vision as ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

Impact of variant allele frequency (VAF) of TP53 alterations and Signatera circulating tumor DNA (ctDNA) monitoring for patients (pts) with advanced urothelial carcinoma (aUC) treated with enfortumab ...

Digital spatial profiling of advanced solid tumors and lymphomas from a phase 1 trial of copanlisib and nivolumab. Using single-cell sequencing to identify endothelial expression of immune checkpoint ...