Experimental work on wet granulation demonstrates the use of dynamic powder characterization to support continuous processing for tablet manufacturing. Bringing the benefits of continuous manufacture ...

The authors review developments in wet granulation using a twin-screw extruder. As a result of changing philosophies towards continuous manufacturing, new equipment is being introduced into ...

Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

Continuous processing as described by the regulatory agencies is the pharmaceutical industry’s area of focus in order to enhance product quality and productivity. It is essential to understand the ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...