A new Northwestern Medicine study has revealed how a common inherited mutation disrupts red blood cell development and sparks inflammation that can lead to leukemia, according to findings published in ...

Add Yahoo as a preferred source to see more of our stories on Google. CXCL12 may help scientists mass-produce artificial red blood cells by triggering key steps in their development. (CREDIT: ...

The production of red blood cells from stem cells has emerged as a transformative approach to address chronic blood shortages and meet the increasing demand for transfusion therapies. By harnessing ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

Polystyrene nanoparticles disrupt red blood cell (RBC) maturation in zebrafish embryos. Nanoparticle exposure increases immature RBCs while reducing mature ones, interfering with heme synthesis.

In a 2023 paper on hypoxia and glucose metabolism, our lab showed how organisms rewire their metabolism to adapt to low oxygen levels-such as those found at high altitudes. One of the most striking ...

Chantez Sanford Jr., 24, of Southfield, says his life has been transformed after undergoing Lyfgenia gene therapy at Children's Hospital of Michigan.

If CXCR4 is removed from the cells, red blood cell development stops at subsequent stages, and bone marrow production drops severely. That loss helps to confirm just how important the CXCL12-CXCR4 ...