An international team of scientists led from Sweden's Karolinska Institutet has for the first time mapped all the genes that are activated in the first few days of a fertilized human egg. The study, ...

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some ...

Microscopy image of a PGA at day 8 showing the early tissues supporting the embryo, including the amniotic sac and the yolk sac-like structures, surrounded by (extra-embryonic) mesoderm tissue.

A recent study in Advanced Science presents a method for studying early human embryology by bioprinting epiblast-like structures from human-induced pluripotent stem cells (hiPSCs). The model forms a ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Using human stem cells, scientists have created human embryo-like structures inside petri dishes. These lab-grown blobs develop multiple structures that mimic a human embryo after implantation into ...

The discovery of a gene essential to early embryonic development sheds light on the preliminary stages of human placenta formation. A team led by scientists from the University of California San Diego ...

At some point in our evolution, we lost the ability to activate a reproductive mechanism called embryonic diapause, which slows development, usually during the blastocyst stage. And so, unlike mammals ...

Shelby is an assistant editor for The Scientist. She earned her PhD from West Virginia University in immunology and microbiology and completed an AAAS Mass Media fellowship. View full profile. Learn ...