A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large-scale gene-silencing structures inside cells, and what happens when that process breaks down. The ...

This article explains how diet creates sustained epigenetic changes that affect long-term health, disease risk, aging, and ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Opus Genetics targets inherited retinal diseases with one-dose AAV gene augmentations. Read why IRD stock is a Buy.

A protein that is a key modulator of fat, glucose and cholesterol levels in the body usually works in tandem with another ...

Researchers at the Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, and the University of Utah School of Medicine, have demonstrated that a gene therapy can ...

A new 3D model shows that Duchenne gene therapy can repair muscle fibers but fails to shut down the signals that drive scarring.

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

Scientists are uncovering how the placenta, long viewed as a temporary pregnancy organ, acts as a powerful biological predictor of lifelong health, linking prenatal environments to future risks of ...