A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

A study published in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilize the cancer genome. Unstable genomes are a fertile playground for cancer ...

(Top) Schematic diagram of the basic unit (Y-motif) of DNA condensates and their binding via sticky-end interaction. (Bottom) A schematic diagram illustrates how DNA condensate formation is regulated ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.

New research predicts the location of DNA sequences that can form structures besides the canonical double helix — non-B DNA — in the recently released telomere-to-telomere genomes of the great apes, ...

The formation of DNA adducts due to flavouring substances, particularly those derived from botanicals, has emerged as a critical area of toxicological research. Many naturally occurring compounds ...

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred to as non-B DNA—have been implicated as regulators of cellular processes ...