As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

Scientists at the Broad Institute and Mass General Brigham have built a generative AI model that creates short DNA segments ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Reporting in Nature, scientists have identified a novel process that protects the ends of chromosomes from incorrectly applied DNA repair. Although DNA repair is a crucial mechanism that can protect a ...

Scientists manufacture many biotherapeutic products in immortalized cell lines, most commonly HEK293. Residual HEK293 DNA in biotherapeutic candidates can harbor tumorigenic or retroviral sequences ...

Researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy found that ...

Precision DNA editing gene therapy achieves deep remissions in aggressive leukemia previously considered incurable.