Scientists have identified key changes to both chromosome structure and gene expression that affect stem cell function during aging. Using fruit flies, they found that these changes led to stem cell ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren’t ...

One of the challenges of working with ancient DNA samples is that damage accumulates over time, breaking up the structure of the double helix into ever smaller fragments. In the samples we’ve worked ...

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Indeed, different kinds of chromosome segment inversions have been ...

The centromere is necessary for the transport of chromosomes during cell division and, therefore, for the correct transmission of genetic information. Most plants and animals have chromosomes with a ...

Jenny Graves receives funding from The Australian Research Council. Men tend to lose the Y chromosome from their cells as they age. But because the Y bears few genes other than for male determination, ...

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Different kinds of chromosome segment inversions have been found in ...